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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 632454Erstellt: 26. Oktober 2026

2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine → 5-Cyclopropyl-6-(2,2,2-trifluoro-1-methyl-ethoxy)-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide

https://huagongshe.com/reaction/632454

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amineHCID 43559251—
Edukt5-Cyclopropyl-6-(1,1,1-trifluoropropan-2-yloxy)picolinic acidHCID 71087435—
Produkt5-Cyclopropyl-6-(2,2,2-trifluoro-1-methyl-ethoxy)-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amideHCID 71093586—

Reaktionsschritte

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(1,1,1-trifluoropropan-2-yloxy)picolinic acid (Example 372 b) and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (CAN 1153831-97-0) as starting materials. MS (EI): m/e=399.5 [M+H]+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09321727B2
Quelldatensatzuspto-grants-2016_04
ORD IDord-de2c55b460154b638a6d25d9cd53c924
Quellennotizuspto-grants-2016_04