HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → 4-(aminomethyl)-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | 4-Chloro-3-(pyridin-2-yl)aniline | HCID 40151925 | — |
| Edukt | BOC-4-(aminomethyl)benzoic acid | HCID 66878017 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 4-(aminomethyl)-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzamide | HCID 66877992 | — |
Reaktionsschritte
Procedure G was used to couple BOC-4-(aminomethyl)benzoic acid (48 mg) with 4-chloro-3-(pyridin-2-yl)aniline (35 mg). The crude reaction mixture was treated with TFA (1 mL) containing trace amounts of water for 1 h. The reaction mixture was concentrated to yield 4-(aminomethyl)-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzamide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09321761B2 |
| Quelldatensatz | uspto-grants-2016_04 |
| ORD ID | ord-5465a48a4fa54ad49fe613e40b89cb13 |
| Quellennotiz | uspto-grants-2016_04 |