HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Azide → 2-Phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Azide | HCID 33557 | — |
| Edukt | 2-Phenoxy-2-oxo-6-iodomethyl-1,2-oxaphosphorinane | HCID 19793129 | — |
| Katalysator | Tetrabutylammonium Bromide | HCID 74236 | — |
| Lösungsmittel | Benzene dimethylformamide | HCID 19608675 | — |
| Produkt | 2-Phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane | HCID 19793120 | 96% |
Reaktionsschritte
A suspension containing two equivalents of sodium azide, one equivalent of the above-prepared iodonated oxaphosphorinane and a catalytic amount of about 0.1 equivalent of tetrabutylammonium bromide in benzene/DMF (1:1) was heated to 60-80 degrees C. for 16 hours to produce 2-phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane in 96 percent yield as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05248611 |
| Quelldatensatz | uspto-grants-1993_09 |
| ORD ID | ord-e5f02821feab4e68bc5f37db01f810ce |
| Quellennotiz | uspto-grants-1993_09 |