N-cyclopropyl-6-(trimethylstannyl)pyrazin-2-amine → 5-(3-(6-(cyclopropylamino)pyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-N-(4-methoxybenzyl)-1,3,4-thiadiazol-2-amine

Reaktionsgleichung

I[C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:11]3[S:15][C:14]([NH:16][CH2:17][C:18]4[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=4)=[N:13][N:12]=3)[CH:9]=2)[N:4]([S:26]([C:29]2[CH:35]=[CH:34][C:32]([CH3:33])=[CH:31][CH:30]=2)(=[O:28])=[O:27])[CH:3]=1.[CH:36]1([NH:39][C:40]2[CH:45]=[N:44][CH:43]=[C:42]([Sn](C)(C)C)[N:41]=2)[CH2:38][CH2:37]1>CN(C=O)C.C(Cl)Cl.[Cu]I.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[CH:36]1([NH:39][C:40]2[N:41]=[C:42]([C:2]3[C:10]4[C:5](=[CH:6][CH:7]=[C:8]([C:11]5[S:15][C:14]([NH:16][CH2:17][C:18]6[CH:19]=[CH:20][C:21]([O:24][CH3:25])=[CH:22][CH:23]=6)=[N:13][N:12]=5)[CH:9]=4)[N:4]([S:26]([C:29]4[CH:35]=[CH:34][C:32]([CH3:33])=[CH:31][CH:30]=4)(=[O:28])=[O:27])[CH:3]=3)[CH:43]=[N:44][CH:45]=2)[CH2:38][CH2:37]1