1-Phenyl-3-pentene → 2-(2-n-Propoxy-5-Morpholinosulfonylphenyl)-8-(5-Phenyl-3-Penten-3-yl)Quinazolin-4(3H)-One
Reaktionsgleichung
[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)(=[O:13])=[O:12])=[CH:7][C:6]=1[C:20]1[NH:29][C:28](=[O:30])[C:27]2[C:22](=[C:23](Br)[CH:24]=[CH:25][CH:26]=2)[N:21]=1)[CH2:2][CH3:3].[C:32]1([CH2:38][CH2:39][CH:40]=[CH:41][CH3:42])[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)(=[O:13])=[O:12])=[CH:7][C:6]=1[C:20]1[NH:29][C:28](=[O:30])[C:27]2[C:22](=[C:23]([C:40](=[CH:39][CH2:38][C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)[CH2:41][CH3:42])[CH:24]=[CH:25][CH:26]=2)[N:21]=1)[CH2:2][CH3:3]Komponenten
3
Versuchsvorschrift
The title compounds are prepared analogously to the method of Example 1, starting with 2-(2-n-propoxy-5-morpholinosulfonylphenyl)-8-bromoquinazolin-4(3H)-one and 5-phenyl-2-pentene, respectively.
Quellen und Nachweise
- ORD-Eintrag
- ord-50226642bad14d769d46daa2f7bf9359