Diethyl ethylmalonate → 2-Amino-2-ethyl-4-(4-octylphenyl)butanol

HRID 635478Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 635478
C([O:4][CH2:5][C:6]([NH:26]C(=O)C)([CH2:24][CH3:25])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:11][CH:10]=1)(=O)C.C(OC(=O)C(CC)C(OCC)=O)C>>[NH2:26][C:6]([CH2:24][CH3:25])([CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:13][CH:14]=1)[CH2:5][OH:4]

Komponenten

3

Edukt 2

HCID 8610Diethyl ethylmalonateHCID 53718772HCID 53718772, Verbindung

Produkt 1

HCID 226187412-Amino-2-ethyl-4-(4-octylphenyl)butanol

Versuchsvorschrift

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is subjected to reduction in the same manner as working example 2 (7) and then hydrolysis in the same manner as working example 78 to give the subject compound.

Aufarbeitung

  1. customobtained
  2. customhydrolysis in the same manner
  3. customto give the subject compound

Quellen und Nachweise

ORD-Eintrag
ord-3d73f6e20225411fb67d8301ad89e7e7
Quelldatensatz
uspto-grants-2001_02
Patentnummer
US06187821B1

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