4-Fluorobenzaldehyde → 4-Fluorobenzoyl chloride

HRID 635541

Reaktionsgleichung

Reaktionsgleichung von HRID 635541
Cl[C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[F:11])[C:5]([Cl:7])=[O:6].FC1C=CC(C=O)=CC=1>>[F:11][C:10]1[CH:9]=[CH:8][C:4]([C:5]([Cl:7])=[O:6])=[CH:3][CH:2]=1

Komponenten

3

Edukt 2

HCID 680234-FluorobenzaldehydeHCID 27365483-Chloro-4-fluorobenzoyl Chloride

Produkt 1

HCID 678794-Fluorobenzoyl chloride

Versuchsvorschrift

The present invention relates to a process for the preparation of 3-chloro-4-fluorobenzoyl chloride which comprises reacting 4-fluorobenzaldehyde with a chlorinating agent in the presence of a free-radical initiator in the presence or absence of a solvent at from −20 to 200° C. to give 4-fluorobenzoyl chloride, and reacting the 4-fluorobenzoyl chloride with a chlorinating agent in the presence of a chlorination catalyst in the presence or absence of a solvent at from −20 to 200° C. to give 3-chloro-4-fluorobenzoyl chloride.

Aufarbeitung

  1. customat from −20 to 200° C.

Quellen und Nachweise

ORD-Eintrag
ord-abca684131fd468f8c669f5289f0ec28
Quelldatensatz
uspto-grants-2001_02
Patentnummer
US06187952B1

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