2-Fluoronicotinic acid → HCID 21255180, Verbindung

Beteiligte Stoffe

Reaktionsschritte

N-(2-Fluoronicotinoyl)thiazole-4-carboxylic acid is prepared as described in Example 5 from 11.03 g of thiazole-4-carboxylic acid and 11.7 g of 2-fluoronicotinic acid. 8.7 g of N-(2-fluoronicotinoyl)thiazole-4-carboxylic acid are thus obtained in the form of a cream solid. (Rf=0.33; thin layer chromatography on silica gel; eluent: ethyl acetate/acetic acid, 90/10 by volume).

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