2-Chloronicotinoyl chloride → HCID 21255137, Verbindung
Reaktionsgleichung
[CH3:1][CH2:2][O:3][C:4]([CH:6]1[NH:10][CH2:9][S:8][CH2:7]1)=[O:5].Cl.[Cl:12][C:13]1[N:21]=[CH:20][CH:19]=[CH:18][C:14]=1[C:15](Cl)=[O:16]>>[Cl:12][C:13]1[N:21]=[CH:20][CH:19]=[CH:18][C:14]=1[C:15]([N:10]1[CH:6]([C:4]([O:3][CH2:2][CH3:1])=[O:5])[CH2:7][S:8][CH2:9]1)=[O:16]Komponenten
3
Versuchsvorschrift
Ethyl N-(2-chloronicotinoyl)thiazolidine-4-carboxylate is prepared as described in Example 5, from 23 g of ethyl L-thiazolidine-4-carboxylate hydrochloride and 20.4 g of 2-chloronicotinoyl chloride. 27 g of ethyl N-(2-chloronicotinoyl)thiazolidine-4-carboxylate are thus obtained in the form of a yellow oil, employed crude.
Aufarbeitung
- customEthyl N-(2-chloronicotinoyl)thiazolidine-4-carboxylate is prepared