Benzenesulfonyl chloride → HCID 70224730, Verbindung
Reaktionsgleichung
[CH:1]12[CH:6]([N:7]3[C:11](=[O:12])[C:10]([CH2:19][C:20]4[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=4)([CH2:13][C:14]4[CH:18]=[CH:17][S:16][CH:15]=4)[NH:9][C:8]3=[CH:26][C:27]([C:29]3[CH:36]=[CH:35][C:32]([C:33]#[N:34])=[CH:31][CH:30]=3)=[O:28])[CH:5]1[CH2:4][NH:3][CH2:2]2.[C:37]1([S:43](Cl)(=[O:45])=[O:44])[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1>>[C:37]1([S:43]([N:3]2[CH2:4][CH:5]3[CH:1]([CH:6]3[N:7]3[C:11](=[O:12])[C:10]([CH2:19][C:20]4[CH:21]=[CH:22][N:23]=[CH:24][CH:25]=4)([CH2:13][C:14]4[CH:18]=[CH:17][S:16][CH:15]=4)[NH:9][C:8]3=[CH:26][C:27]([C:29]3[CH:30]=[CH:31][C:32]([C:33]#[N:34])=[CH:35][CH:36]=3)=[O:28])[CH2:2]2)(=[O:45])=[O:44])[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1Komponenten
3
Versuchsvorschrift
According to the procedure of Example 13, the title compound of 37A (60 mg, 0.12 mmol) and benzenesulfonyl chloride (0.023 ml, 0.18 mmol) were reacted to generate the title compound as a white solid (58 mg, 0.091 mmol, 76% yield).
Quellen und Nachweise
- ORD-Eintrag
- ord-894f1c63cabc4c6896f0845f3f60be04
- Quelldatensatz
- uspto-grants-2001_02
- Patentnummer
- US06194438B1
Notizen zur Reaktion
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