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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 637378Erstellt: 25. Oktober 2026

Hydrochloric Acid → 2-cyclopentyl-1-[p-(N,N-dimethyl-2-aminoethoxy)phenyl]-1-(p-hydroxyphenyl)-1-butanol

https://huagongshe.com/reaction/637378

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktHydrochloric AcidHCID 313—
Edukt(2-(4-Bromophenoxy)ethyl)dimethylamineHCID 213877—
Eduktalpha-Cyclopentyl-p-hydroxybutyrophenoneHCID 13175265—
LösungsmittelEthanolHCID 702—
Produkt2-cyclopentyl-1-[p-(N,N-dimethyl-2-aminoethoxy)phenyl]-1-(p-hydroxyphenyl)-1-butanolHCID 20256938—

Reaktionsschritte

2-cyclopentyl-1-[p-(N,N-dimethyl-2-aminoethoxy)phenyl]-1-(p-hydroxyphenyl)-1-butanol, which was prepared from α-cyclopentyl-p-hydroxybutyrophenone and p-(N,N-dimethyl-2-aminoethoxy) bromobenzene according to the procedure of example 3, was dehydrated in ethanol in the presence of hydrochloric acid. The product was recrystallized from n-hexane, mp. 112°-120° C. and was found to be an 1:1 mixture of E- and Z-isomers.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04556677
Quelldatensatzuspto-grants-1985_12
ORD IDord-4fcd5461932b4ca9abf4342ca40471a3
Quellennotizuspto-grants-1985_12