HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-methylpiperidine-4-carboxamide → 1-[6-Chloro-2-(4-fluorophenyl)-4-quinolinyl]-N-methyl-4-piperidinecarboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-methylpiperidine-4-carboxamide | HCID 2760460 | — |
| Edukt | 4,6-Dichloro-2-(4-fluorophenyl)quinoline | HCID 13603901 | — |
| Lösungsmittel | Pyridine water | HCID 66926435 | — |
| Produkt | 1-[6-Chloro-2-(4-fluorophenyl)-4-quinolinyl]-N-methyl-4-piperidinecarboxamide | HCID 13603927 | — |
Reaktionsschritte
The named compound was made in a manner analogous to that of Example 4(c) using 4,6-dichloro-2-(4-fluorophenyl)quinoline, prepared as in Example 20, and N-methylisonipecotamide as starting materials. It was obtained as off-white needles, mp 260°-265° dec on recrystallization from pyridine/water.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04560692 |
| Quelldatensatz | uspto-grants-1985_12 |
| ORD ID | ord-99b0e3e06ca044a98979c9cafc1f2c07 |
| Quellennotiz | uspto-grants-1985_12 |