Ethyl cyanoacetate → 2-cyano-N-(2-methoxyethyl)acetamide
Reaktionsgleichung
[C:1]([CH2:3][C:4]([O:6]CC)=O)#[N:2].[CH3:9][O:10][CH2:11][CH2:12][NH2:13]>C(O)C>[C:1]([CH2:3][C:4]([NH:13][CH2:12][CH2:11][O:10][CH3:9])=[O:6])#[N:2]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
0.5 g (4.42 mmol) Ethyl cyanoacetate and 0.37 g (4.86 mmol) 2-methoxyethylamine are dissolved in 10 ml ethanol and stirred at reflux overnight. After cooling down to room temperature, the solvent is removed in vacuo and the product is crystallised from ethanol/diethylether.
Aufarbeitung
- temperatureat reflux overnight
- customthe solvent is removed in vacuo
- customthe product is crystallised from ethanol/diethylether
Quellen und Nachweise
- ORD-Eintrag
- ord-7cfbd73ec4d34dc380ac579d243f96ea
- Quelldatensatz
- uspto-grants-2010_04
- Patentnummer
- US07691854B2
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