HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
L-Leucinol → 6-(2-Methoxy-ethoxy)-5-pyrrolidin-1-yl-pyrazine-2-carboxylic acid ((S)-1-hydroxymethyl-3-methyl-butyl)-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | L-Leucinol | HCID 111307 | — |
| Edukt | 6-Propoxy-5-pyrrolidin-1-yl-pyrazine-2-carboxylic acid ((S)-1-hydroxymethyl-3-methyl-butyl)-amide | HCID 24831258 | — |
| Edukt | 6-(2-Methoxy-ethoxy)-5-pyrrolidin-1-yl-pyrazine-2-carboxylic acid | HCID 68565209 | — |
| Produkt | 6-(2-Methoxy-ethoxy)-5-pyrrolidin-1-yl-pyrazine-2-carboxylic acid ((S)-1-hydroxymethyl-3-methyl-butyl)-amide | HCID 24831416 | — |
Reaktionsschritte
In analogy to the procedure described for the synthesis of 6-propoxy-5-pyrrolidin-1-yl-pyrazine-2-carboxylic acid ((S)-1-hydroxymethyl-3-methyl-butyl)-amide (example 10, step d) the title compounds was prepared from 6-(2-methoxy-ethoxy)-5-pyrrolidin-1-yl-pyrazine-2-carboxylic acid and (S)-2-amino-4-methyl-pentan-1-ol (commercially available). m/z (ES+): 367.3 (M+H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07691863B2 |
| Quelldatensatz | uspto-grants-2010_04 |
| ORD ID | ord-f141c88bd95d47b9a013a51da8171121 |
| Quellennotiz | uspto-grants-2010_04 |