Methyl 2-amino-2-ethylbutanoate → 2-Ethyl-2-{[6-(2-methoxy-ethoxy)-5-morpholin-4-yl-pyrazine-2-carbonyl]-amino}-butyric acid methyl ester

Beteiligte Stoffe

Reaktionsschritte

In analogy to the procedure described for the synthesis of 6-propoxy-5-pyrrolidin-1-yl-pyrazine-2-carboxylic acid ((S)-1-hydroxymethyl-3-methyl-butyl)-amide (example 10, step d) the title compounds was prepared from 6-(2-methoxy-ethoxy)-5-morpholin-4-yl-pyrazine-2-carboxylic acid and 2-amino-2-ethyl-butyric acid methyl ester (European Journal of Medicinal Chemistry 1984, 19, 261). m/z (ES+): 411.5 (M+H).

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