Ethyl m-toluate → [4-(2-Diethylamino-ethoxy)-phenyl]-[4-(3-m-tolyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-amine
Reaktionsgleichung
C(O[C:4](=O)[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[CH:6]=1)C.ClC1C=CC(C2[C:24]([C:25]3[CH:30]=[CH:29][N:28]=[C:27]([NH:31][C:32]4[CH:37]=[CH:36][C:35]([O:38][CH2:39][CH2:40][N:41]([CH2:44][CH3:45])[CH2:42][CH3:43])=[CH:34][CH:33]=4)[N:26]=3)=[CH:23][NH:22][N:21]=2)=CC=1>>[CH2:44]([N:41]([CH2:42][CH3:43])[CH2:40][CH2:39][O:38][C:35]1[CH:36]=[CH:37][C:32]([NH:31][C:27]2[N:26]=[C:25]([C:24]3[C:4]([C:5]4[CH:6]=[C:7]([CH3:11])[CH:8]=[CH:9][CH:10]=4)=[N:21][NH:22][CH:23]=3)[CH:30]=[CH:29][N:28]=2)=[CH:33][CH:34]=1)[CH3:45]Komponenten
3
Versuchsvorschrift
The title compound is prepared as described in Example 1 using ethyl-3-methylbenzoate (Aldrich 25,305-7) and 4-(2-diethylamino-ethoxy)-phenylamine (see Example 3).
Quellen und Nachweise
- ORD-Eintrag
- ord-c659f63bfd2b48758e5499ffcbae0613
- Quelldatensatz
- uspto-grants-2010_04
- Patentnummer
- US07691855B2
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