5-Iodoisatin → HCID 178517197, Verbindung

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

Following the general method as outlined in Example 1, into a suspension of 5-iodo-1H-indole-2,3-dione in acetic acid was added 3-nitrobenzohydrazide. After stirring at 100° C., the reaction mixture was cooled to rt and a yellow solid precipitated out. Filtration on a fritté, washing with AcOH, water and drying under vacuo at 60° C. overnight gave 176 mg of the title compound (81%) as a orange solid in 98.4% purity by HPLC (Rt: 5.61, gradient of 10 min, MaxPlot detection between 230 and 400 nm).

Herkunft & Nachweise