4-Aminobenzoic acid hydrazide → HCID 178507641, Verbindung

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

Following the general method as outlined in Example 1, into a suspension of 5-iodo-1H-indole-2,3-dione in acetic acid was added 4-aminobenzohydrazide. After stirring at 100° C., the reaction mixture was cooled to rt and a yellow solid precipitated out. Filtration on a fritté, washing with AcOH, water and drying under vacuo at 60° C. overnight gave 395 mg of the title compound (97%) as a yellow solid in 99.2% purity by HPLC (Rt: 4.41, gradient of 10 min, MaxPlot detection between 230 and 400 nm).

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