1-(Bromomethyl)naphthalene → 4-Methyl-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid

HRID 642617Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 642617
C[O:2][C:3]([C:5]1[NH:6][C:7]2[C:12]([CH:13]=1)=[C:11]([CH3:14])[CH:10]=[CH:9][CH:8]=2)=[O:4].Br[CH2:16][C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=[CH:19][CH:18]=1>>[CH3:14][C:11]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:12]=1[CH:13]=[C:5]([C:3]([OH:2])=[O:4])[N:6]2[CH2:16][C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=[CH:19][CH:18]=1

Komponenten

3

Edukt 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 4714967methyl 4-methyl-1H-indole-2-carboxylate

Produkt 1

HCID 589002764-Methyl-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid

Versuchsvorschrift

Using general procedure B, 4-methyl-1H-indole-2-carboxylic acid methyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a pale yellow solid. MS: 314.1 ([M−H]−).

Aufarbeitung

  1. customthe product obtained

Quellen und Nachweise

ORD-Eintrag
ord-920fa18dfa98483ab38d44d82c76b9ca
Quelldatensatz
uspto-grants-2010_04
Patentnummer
US07696240B2

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