Ethyl indole-2-carboxylate → HCID 58900224, Verbindung
Reaktionsgleichung
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:5])C.Br[CH2:16][C:17]1[C:26]2[C:21](=[CH:22][C:23]([O:27][CH:28]([CH3:30])[CH3:29])=[CH:24][CH:25]=2)[CH:20]=[CH:19][CH:18]=1>>[CH:28]([O:27][C:23]1[CH:22]=[C:21]2[C:26](=[CH:25][CH:24]=1)[C:17]([CH2:16][N:7]1[C:8]3[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:14]=[C:6]1[C:4]([OH:3])=[O:5])=[CH:18][CH:19]=[CH:20]2)([CH3:30])[CH3:29]Komponenten
3
Versuchsvorschrift
Using general procedure B, 1H-indole-2-carboxylic acid ethyl ester was coupled with 1-bromomethyl-6-isopropoxy-naphthalene and the product obtained was hydrolyzed to give 1-(6-isopropoxy-naphthalen-1-ylmethyl)-1H-indole-2-carboxylic acid as a white solid. MS: 358.0 ([M−H]−).
Aufarbeitung
- customthe product obtained
Quellen und Nachweise
- ORD-Eintrag
- ord-f1baaa59c91c44609a31018d26202ce3
- Quelldatensatz
- uspto-grants-2010_04