Methyl 3-(bromomethyl)benzoate → 3-(2'-Nitro-biphenyl-4-yloxymethyl)-benzoic acid
Reaktionsgleichung
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[N+:14]([O-:16])=[O:15])=[CH:4][CH:3]=1.C[O:18][C:19](=[O:28])[C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH2:26]Br)[CH:21]=1>>[N+:14]([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=1[C:5]1[CH:6]=[CH:7][C:2]([O:1][CH2:26][C:22]2[CH:21]=[C:20]([CH:25]=[CH:24][CH:23]=2)[C:19]([OH:28])=[O:18])=[CH:3][CH:4]=1)([O-:16])=[O:15]Komponenten
3
Versuchsvorschrift
3-(2′-Nitro-biphenyl-4-yloxymethyl)-benzoic acid was prepared using general procedure A from 4-hydroxy-2′-nitrobiphenyl (available from TCI America, Portland, Oreg.) and 3-(bromomethyl)benzoic acid methyl ester (available from Lancaster Synthesis Ltd. Morcambe, Lancashire, UK). Yield: 82 mg. Mass spectrum (ES) MH+=350.
Quellen und Nachweise
- ORD-Eintrag
- ord-0194ee4327204b7289dda62f78f56c77
- Quelldatensatz
- uspto-grants-2010_04