2-Chloro-4-nitrotoluene → 1-(Bromomethyl)-2-chloro-4-nitrobenzene

Beteiligte Stoffe

Reaktionsschritte

A mixture of 2-chloro-4-nitrotoluene (0.20 g, 1.17 mmol), N-bromosuccinimide (0.228 g, 1.28 mmol) and benzoyl peroxide (0.014 g, 0.058 mmol) in tetrachloromethane (7 mL) was irradiated (500 W lamp) at reflux overnight. The reaction mixture was concentrated to give a yellow oil/solid (0.391 g) which was used directly in the next step without further purification.

Herkunft & Nachweise