Bis(2-Methoxyethyl)amine → N,N-Bis-(2-methoxy-ethyl)-2-piperazin-1-yl-acetamide dihydrochloride

HRID 645763

Reaktionsgleichung

Reaktionsgleichung von HRID 645763
C(OC(N1CCNCC1)=O)(C)(C)C.[Cl:14]CC(Cl)=O.[CH3:19][O:20][CH2:21][CH2:22][NH:23][CH2:24][CH2:25][O:26][CH3:27].[ClH:28].Cl.COCC(N[C:36](=[O:44])[CH2:37][N:38]1[CH2:43][CH2:42][NH:41][CH2:40][CH2:39]1)C>>[ClH:14].[ClH:28].[CH3:19][O:20][CH2:21][CH2:22][N:23]([CH2:24][CH2:25][O:26][CH3:27])[C:36](=[O:44])[CH2:37][N:38]1[CH2:43][CH2:42][NH:41][CH2:40][CH2:39]1

Komponenten

5

Edukt 4

HCID 2383Bis(2-Methoxyethyl)amineHCID 6577Chloroacetyl chlorideHCID 143452tert-Butyl piperazine-1-carboxylateHCID 67245894N-(2-methoxy-1-methylethyl)-2-piperazin-1-yl-acetamide dihydrochloride

Produkt 1

HCID 67246429N,N-Bis-(2-methoxy-ethyl)-2-piperazin-1-yl-acetamide dihydrochloride

Versuchsvorschrift

N,N-Bis-(2-methoxy-ethyl)-2-piperazin-1-yl-acetamide dihydrochloride was prepared from 1-tert-butyloxycarbonyl-piperazine, chloroacetylchloride and N,N-bis-(2-methoxy-ethyl)amine in an analogous manner as described for the preparation of N-(2-methoxy-1-methyl-ethyl)-2-piperazin-1-yl-acetamide dihydrochloride (example 40).

Quellen und Nachweise

ORD-Eintrag
ord-3db4dcb7c23d4c1e8e0e0f766228d605
Quelldatensatz
uspto-grants-2010_04
Patentnummer
US07705007B2

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