Benzaldehyde → 2-[(3,5-Dimethyl-1H-indol-2-yl)-phenyl-methyl]-3-hydroxy-4-methyl-4-p-tolyl-cyclobut-2-enone

HRID 646068Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 646068
[CH3:1][C:2]1([C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][CH:9]=2)[C:5](=[O:6])[CH2:4][C:3]1=[O:7].[CH:15](=O)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[CH3:23][C:24]1[C:32]2[C:27](=[CH:28][CH:29]=[C:30]([CH3:33])[CH:31]=2)[NH:26][CH:25]=1>>[CH3:23][C:24]1[C:32]2[C:27](=[CH:28][CH:29]=[C:30]([CH3:33])[CH:31]=2)[NH:26][C:25]=1[CH:15]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:4]1[C:5](=[O:6])[C:2]([CH3:1])([C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][CH:9]=2)[C:3]=1[OH:7]

Komponenten

4

Edukt 3

HCID 240BenzaldehydeHCID 986153,5-DimethylindoleHCID 68581955HCID 68581955, Verbindung

Produkt 1

HCID 250507062-[(3,5-Dimethyl-1H-indol-2-yl)-phenyl-methyl]-3-hydroxy-4-methyl-4-p-tolyl-cyclobut-2-enone

Versuchsvorschrift

Using general procedure C, 2-methyl-2-p-tolyl-cyclobutane-1,3-dione (from Example 4.1) was reacted with benzaldehyde and 3,5-dimethyl-1H-indole (Lit. 3) to give the title compound as a colorless solid. MS: 420.5 ([M−H]−).

Quellen und Nachweise

ORD-Eintrag
ord-6f1801b75d2c473095242c8f44fcf537
Quelldatensatz
uspto-grants-2010_04
Patentnummer
US07705034B2

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