Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Ammonia | HCID 222 | — |
| Edukt | Methyl 3-aminopyrazinecarboxylate | HCID 72669 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | Aminopyrazine carboxamide | HCID 280292 | 97,7% |
Reaktionsschritte
A suspension of methyl 3-aminopyrazine-2-carboxylate (5 g, 32.6 mmol) and 150 mL of dry methanol saturated with anhydrous ammonia were heated in an autoclave at 110-115° C. for 24 h. Concentration and filtration afforded 3-aminopyrazine-2-carboxamide (4.4 g, 97.7% yield) as a yellow solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US07704995B2 |
|---|
| Quelldatensatz | uspto-grants-2010_04 |
|---|
| ORD ID | ord-18874ded497546f18a4d5fbaeb33b899 |
|---|
| Quellennotiz | uspto-grants-2010_04 |
|---|
