4-Methylpiperidine → 1-(5-Chloro-2-nitro-phenyl)-4-methyl-piperidine

Beteiligte Stoffe

Reaktionsschritte

The procedure of Example 4, step (a) was followed using 0.950 g (5.43 mmol) of 4-chloro-2-fluoronitrobenzene and 1.93 mL (16.3 mmol) of 4-methylpiperidine in 10 mL of EtOH to afford 1.37 g (99%) of the title compound as an orange oil which crystallized on standing: Mass spectrum (ESI, m/z): Calcd. for C12H15ClN2O2, 255.1 (M+H), found 255.0.

Herkunft & Nachweise