4-(Trifluoromethyl)aniline → Valine, N-[4-(trifluoromethyl)phenyl]-
Reaktionsgleichung
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:9]=[CH:8][C:6]([NH2:7])=[CH:5][CH:4]=1.Br[CH:13]([CH:33]([CH3:35])[CH3:34])[C:14]([O:16]C(C#N)C1C=CC=C(OC2C=CC=CC=2)C=1)=[O:15]>>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:9]=[CH:8][C:6]([NH:7][C@H:13]([C:14]([OH:16])=[O:15])[CH:33]([CH3:35])[CH3:34])=[CH:5][CH:4]=1Komponenten
3
Versuchsvorschrift
Following the procedure of Example 6, 4-trifluoromethylaniline is reacted with α-cyano-m-phenoxybenzyl α-bromoisovalerate to yield the α-cyano-m-phenoxybenzyl ester of N-(4-trifluoromethylphenyl)valine, MS m/e 468.2 (M+).
Quellen und Nachweise
- ORD-Eintrag
- ord-43dc9802ea724a8084d1490354e8d8ee
- Quelldatensatz
- uspto-grants-1983_10
- Patentnummer
- US04411912
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