p-Anisoyl chloride → HCID 13371227, Verbindung

HRID 64866

Reaktionsgleichung

Reaktionsgleichung von HRID 64866
[N:1]1([CH2:7][C:8]([N:10]2[CH2:15][CH2:14][O:13][CH2:12][CH2:11]2)=[O:9])[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[C:16]([Cl:26])(=[O:25])[C:17]1[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=1>C(Cl)Cl.C(O)(C)C>[ClH:26].[CH3:24][O:23][C:20]1[CH:21]=[CH:22][C:17]([C:16]([N:4]2[CH2:3][CH2:2][N:1]([CH2:7][C:8]([N:10]3[CH2:11][CH2:12][O:13][CH2:14][CH2:15]3)=[O:9])[CH2:6][CH2:5]2)=[O:25])=[CH:18][CH:19]=1

Komponenten

5

Edukt 2

HCID 7477p-Anisoyl chlorideHCID 1006221-(Morpholinocarbonylmethyl)piperazine

Produkt 1

HCID 13371227HCID 13371227, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3776IsopropanolLösungsmittelHCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

10.25 g of piperazin-1-yl-acetic acid morpholide are cooled to 0° C. in 20 ml of methylene chloride. 8.75 g of anisoyl chloride are added dropwise in the course of 15 minutes. After the mixture has been subsequently stirred for 4 hours, it is diluted with isopropanol, whereupon the colourless product precipitates. It is filtered off with suction and dried.

Aufarbeitung

  1. customprecipitates
  2. filtrationIt is filtered off with suction
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-21ca3ae338254865a0d42275bcf052d1
Quelldatensatz
uspto-grants-1986_09
Patentnummer
US04610984

Verknüpfte Notizen

Wird geladen…