2,6-Dimethyl-4-pyranone → 2,6-Dimethyloxan-4-ol

HRID 650273

Reaktionsgleichung

Reaktionsgleichung von HRID 650273
[CH3:1][C:2]1[O:3][C:4]([CH3:9])=[CH:5][C:6](=[O:8])[CH:7]=1.[H][H]>C(O)C>[CH3:1][CH:2]1[CH2:7][CH:6]([OH:8])[CH2:5][CH:4]([CH3:9])[O:3]1

Komponenten

4

Edukt 2

HCID 138622,6-Dimethyl-4-pyranoneHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 151823572,6-Dimethyloxan-4-olAusbeute 74 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

2,6-Dimethyl-4H-pyran-4-one (5.0 g) in ethanol (40 ml) was hydrogenated under 10% Pd-C (0.5 g) at 10 bar of hydrogen for 2 days. The solution was then evaporated to an oil which was purified by silica-gel MPLC [using a 1:1 mixture of ethyl acetate and hexane as eluant] to give the title product (3.71 g, 74%).

Aufarbeitung

  1. customThe solution was then evaporated to an oil which
  2. customwas purified by silica-gel MPLC [
  3. additiona 1:1 mixture of ethyl acetate and hexane as eluant]

Quellen und Nachweise

ORD-Eintrag
ord-039e7efd8f2f4c5db60a0b7a194d01ed
Quelldatensatz
uspto-grants-2001_08
Patentnummer
US06271383B1

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