Butanimidamide hydrochloride → 4-Phenyl-2-propyl-pyrimidine-5-carboxylic acid

HRID 650623Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 650623
C([O:3][C:4](=[O:18])[C:5]([C:10](=O)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[CH:6]N(C)C)C.Cl.[C:20]([NH2:25])(=[NH:24])[CH2:21][CH2:22][CH3:23]>>[C:11]1([C:10]2[C:5]([C:4]([OH:18])=[O:3])=[CH:6][N:25]=[C:20]([CH2:21][CH2:22][CH3:23])[N:24]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Komponenten

3

Edukt 2

HCID 12828983Butanimidamide hydrochlorideHCID 54499154Ethyl-2-benzoyl-3-dimethylaminopropenoate

Produkt 1

HCID 217124024-Phenyl-2-propyl-pyrimidine-5-carboxylic acid

Versuchsvorschrift

In an analogous manner to that described in example 3b) starting from 2-benzoyl-3-dimethylamino-acrylic acid ethyl ester and butyramidine hydrochloride, followed by saponification as described in example 3c) there was obtained 4-phenyl-2-propyl-pyrimidine-5-carboxylic acid.

Quellen und Nachweise

ORD-Eintrag
ord-6f7a54e20329438e9d7ae5901def92d8
Quelldatensatz
uspto-grants-2001_08
Patentnummer
US06274588B1

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