HCID 13714726, Verbindung → HCID 13714728, Verbindung

HRID 65094Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 65094
[CH:1]([C:4]([C:24]1[CH:29]=[C:28]([O:30][CH3:31])[C:27]([O:32][CH3:33])=[C:26]([O:34][CH3:35])[CH:25]=1)([CH2:7][CH2:8][CH2:9][NH:10][CH2:11][CH2:12][CH2:13][O:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[N+:21]([O-])=O)[C:5]#[N:6])([CH3:3])[CH3:2]>CO.[Pt]=O>[CH:1]([C:4]([C:24]1[CH:29]=[C:28]([O:30][CH3:31])[C:27]([O:32][CH3:33])=[C:26]([O:34][CH3:35])[CH:25]=1)([CH2:7][CH2:8][CH2:9][NH:10][CH2:11][CH2:12][CH2:13][O:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[NH2:21])[C:5]#[N:6])([CH3:3])[CH3:2]

Komponenten

4

Edukt 1

HCID 13714726HCID 13714726, Verbindung

Produkt 1

HCID 13714728HCID 13714728, VerbindungAusbeute 97,2 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

4.78 g of alpha-isopropyl-alpha-[3-[N-[3-(2-nitrophenoxy)propyl]amino]propyl]-3,4,5-trimethoxyphenyl-acetonitrile was hydrogenated in 100 ml of methanol over 50 mg of platinum oxide at atmospheric pressure and room temperature. The catalyst was filtered off and filtrate was evaporated to give 4.36 g of desired compound as a pale yellow oil.

Aufarbeitung

  1. filtrationThe catalyst was filtered off
  2. customfiltrate was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-0def383bcd52460d8c89ff77202dcd60
Quelldatensatz
uspto-grants-1986_09
Patentnummer
US04612329

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