HCID 13714730, Verbindung → HCID 13714732, Verbindung

HRID 65097Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 65097
[CH:1]([C:4]([C:25]1[CH:30]=[C:29]([O:31][CH3:32])[C:28]([O:33][CH3:34])=[C:27]([O:35][CH3:36])[CH:26]=1)([CH2:7][CH2:8][CH2:9][N:10]([CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[N+:22]([O-])=O)[CH3:11])[C:5]#[N:6])([CH3:3])[CH3:2]>CO.[Pt]=O>[CH:1]([C:4]([C:25]1[CH:30]=[C:29]([O:31][CH3:32])[C:28]([O:33][CH3:34])=[C:27]([O:35][CH3:36])[CH:26]=1)([CH2:7][CH2:8][CH2:9][N:10]([CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[NH2:22])[CH3:11])[C:5]#[N:6])([CH3:3])[CH3:2]

Komponenten

4

Edukt 1

HCID 13714730HCID 13714730, Verbindung

Produkt 1

HCID 13714732HCID 13714732, VerbindungAusbeute 105,2 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

0.92 g of alpha-isopropyl-alpha-[3-[N-[3-(2-nitrophenoxy)propyl]-N-methylamino]propyl]-3,4,5-trimethoxyphenylacetonitrile was hydrogenated in 20 ml of methanol over 10 mg of platinum oxide at atmospheric pressure and room temperature. The catalyst was filtered off and filtrate was evaporated to give 0.91 g of the desired compound as a yellow oil. The oxalate of this compound was obtained in the usual manner.

Aufarbeitung

  1. filtrationThe catalyst was filtered off
  2. customfiltrate was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-2f0e8264333b4780b3d6f70d45b41568
Quelldatensatz
uspto-grants-1986_09
Patentnummer
US04612329

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