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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 651661Erstellt: 26. Oktober 2026

6-Chlorobenzo[b]thiophene-2-sulfonyl chloride → 6-Chloro-benzo[b]thiophene-2-sulfonic acid (2-oxo-1-prop-2-ynyl-pyrrolidin-3-(s)-yl)amide

https://huagongshe.com/reaction/651661

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt6-Chlorobenzo[b]thiophene-2-sulfonyl chlorideHCID 15158641—
Edukt3-(S)-amino-1-prop-2-ynyl-pyrrolidin-2-one hydrochlorideHCID 20680730—
Produkt6-Chloro-benzo[b]thiophene-2-sulfonic acid (2-oxo-1-prop-2-ynyl-pyrrolidin-3-(s)-yl)amideHCID 53892522—

Reaktionsschritte

The title compound is prepared as described in EXAMPLE 1, Part K using 6-chloro-benzo[b]thiophene-2-sulfonyl chloride and 3-(S)-amino-1-prop-2-ynyl-pyrrolidin-2-one hydrochloride as starting material. The crude product is isolated as a beige foam and used in the subsequent step without further purification.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06281227B1
Quelldatensatzuspto-grants-2001_08
ORD IDord-05187c3376004192a615c0c17db4dc1e
Quellennotizuspto-grants-2001_08