Thionyl Chloride → 3-(Chloromethyl)-1,1'-biphenyl

Beteiligte Stoffe

Reaktionsschritte

A solution of 50 mg of 3-hydroxymethylbiphenyl in 1.5 mL thionyl chloride was heated at reflux temperature for 4 hr, cooled to room temperature and the solvent removed by evaporation under reduced pressure to yield 45 mg of 3-chloromethylbiphenyl which was used in the next step without further purification or characterization.

Herkunft & Nachweise