HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Malononitrile → Dihydro-2H-pyran-4,4(3H)-dicarbonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Malononitrile | HCID 8010 | — |
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 1,1'-Oxybis(2,2-dichloroethane) | HCID 62383 | — |
| Lösungsmittel | Acetonitrile | HCID 6342 | — |
| Produkt | Dihydro-2H-pyran-4,4(3H)-dicarbonitrile | HCID 14537194 | — |
Reaktionsschritte
According to Flowchart B dichloroethyl ether (7) and malononitrile (8) are reacted with potassium carbonate in acetonitrile at reflux, giving tetrahydro-4H-pyran-4,4-dicarbonitrile (9) which is then reacted with 1N borane in tetrahydrofuran followed by treatment with hydrochloric acid, giving tetrahydro-4H-pyran-4,4-dimethanamine dihydrochloride (10) which is then reacted with sodium acetate and potassium tetrachloroplatinate in water, giving the product (11).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06281365B1 |
| Quelldatensatz | uspto-grants-2001_08 |
| ORD ID | ord-9feac1c7d68d41e1a05a382e62012bcf |
| Quellennotiz | uspto-grants-2001_08 |