Hydrogen Peroxide → 28893-44-9

HRID 651944

Reaktionsgleichung

Reaktionsgleichung von HRID 651944
[CH3:1][CH:2]([CH2:4][CH2:5][CH2:6][C@H:7]([C@@H:9]1[C@:26]2([CH3:27])[C@H:12]([C@H:13]3[C@H:23]([CH2:24][CH2:25]2)[C@:21]2([CH3:22])[C:16](=[CH:17][C:18](=[O:28])[CH:19]=[CH:20]2)[CH:15]=[CH:14]3)[CH2:11][CH2:10]1)[CH3:8])[CH3:3].[OH-:29].[Na+].OO>C(O)C>[O:29]1[C@H:19]2[C:18](=[O:28])[CH:17]=[C:16]3[C@:21]([CH3:22])([C@@H:20]12)[C@@H:23]1[C@H:13]([C@H:12]2[C@:26]([CH3:27])([CH2:25][CH2:24]1)[C@@H:9]([C@H:7]([CH3:8])[CH2:6][CH2:5][CH2:4][CH:2]([CH3:1])[CH3:3])[CH2:10][CH2:11]2)[CH:14]=[CH:15]3

Komponenten

5

Edukt 3

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 1073901,4,6-Cholestatrien-3-one

Produkt 1

HCID 1391110828893-44-9

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

The trienone from (a) (1 gm) in ethanol (50 mls) at 0° was treated with 10% aqueous sodium hydroxide (0.25 ml) and 30% aqueous H2O2 (2.5 ml). The mixture was stored at 5° overnight and then the resulting epoxide was filtered off, washed with aqueous alcohol and dried to afford the title compound (0.86 mgs). Recrystallization from ethanol gave colourless needles, melting point 107°-109°.

Aufarbeitung

  1. filtrationthe resulting epoxide was filtered off
  2. washwashed with aqueous alcohol
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-b723e16e0e7c40a996b359e9ea7317d4
Quelldatensatz
uspto-grants-1987_06
Patentnummer
US04670190

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