Hydrochloric Acid → 1-(4-Hydroxyphenyl)-2-[2-(isochroman-1-yl)-1-methylethylamino]-1-propanol

Beteiligte Stoffe

Reaktionsschritte

An oily product was obtained in the same manner as in Example 1, using (isochroman-1-yl)acetone and 2-amino-1-(4-hydroxyphenyl)-1-propanol [J. Med. Chem., 14, 148 (1971)]. The product was dissolved in anhydrous methanol, and concentrated hydrochloric acid was added thereto. The solvent was evaporated off to give a hydrochloride. The hydrochloride was then washed with ether to give Compound 24 as crystals in a yield of 72%.

Herkunft & Nachweise