Monobasic potassium phosphate → Ribavirin

HRID 65430

Reaktionsgleichung

Reaktionsgleichung von HRID 65430
[NH:1]1[CH:5]=[N:4][C:3]([C:6]([NH2:8])=[O:7])=[N:2]1.P([O-])(O)(O)=O.[K+].[O:15]=[CH:16][C@@H:17]([C@@H:19]([C@@H:21]([CH2:23][OH:24])[OH:22])[OH:20])O>>[CH:5]1[N:1]([C@@H:23]2[O:24][C@H:17]([CH2:16][OH:15])[C@@H:19]([OH:20])[C@H:21]2[OH:22])[N:2]=[C:3]([C:6]([NH2:8])=[O:7])[N:4]=1

Komponenten

4

Edukt 3

HCID 516951Monobasic potassium phosphateHCID 5311110Aldehydo-D-riboseHCID 178513825HCID 178513825, Verbindung

Produkt 1

HCID 37542Ribavirin

Versuchsvorschrift

To each suspension was added each 1 ml of an aqueous solution (pH 7.0) containing 20 mM 1,2,4-triazole-3-carboxamide, 20 ml of various ribose donors as shown in Table 10 and 25 mM monopotassium dihydrogen phosphate, and the reaction was carried out at 60° C. for 20 hours. After the reaction, the microbial cells were removed by centrifugation and the supernatant was analyzed to give the results of ribavirin yields as shown in Table 10.

Aufarbeitung

  1. customAfter the reaction
  2. customthe microbial cells were removed by centrifugation
  3. customto give the

Quellen und Nachweise

ORD-Eintrag
ord-0e3c0a1ca247400ea7570e83d8abcee8
Quelldatensatz
uspto-grants-1986_09
Patentnummer
US04614719

Verknüpfte Notizen

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