(1S,4S)-4-(3-pyridyl)-2-cyclopenten-1-ol → (1R,3R)-3-(3-pyridyl)cyclopentanol

Beteiligte Stoffe

Reaktionsschritte

A mixture of (1S,4S)-4-(3-pyridyl)-2-cyclopenten-1-ol (1.86 g, 11.5 mmol) and 10% Pd/C (186 mg) in EtOH (35 mL) was stirred under hydrogen atmosphere for 3 h. The catalyst was removed by filtration over Celite and the filtrate was concentrated in vacuo. (1R,3R)-3-(3-pyridyl)cyclopentanol (1.82 g, 97%) was yield as yellow oil.

Herkunft & Nachweise