Hydrochloric Acid → 1-(1-Benzothiophen-4-yl)piperazine hydrochloride

HRID 655635Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 655635
[ClH:1].[S:2]1[CH:6]=[CH:5][C:4]2[C:7]([N:11]3[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]3)=[CH:8][CH:9]=[CH:10][C:3]1=2>CO>[ClH:1].[S:2]1[CH:6]=[CH:5][C:4]2[C:7]([N:11]3[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]3)=[CH:8][CH:9]=[CH:10][C:3]1=2

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 210731871-(Benzo[b]thiophen-4-yl)piperazine

Produkt 1

HCID 574825411-(1-Benzothiophen-4-yl)piperazine hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

Then, 3.7 ml of concentrated hydrochloric acid was added to a methanol solution of 9.5 g of 1-benzo[b]thiophen-4-yl-piperazine, and the solvent was evaporated under reduced pressure. Ethyl acetate was added to the obtained residue and precipitated crystals were obtained by filtration. Recrystallization was performed from methanol to obtain 1-benzo[b]thiophen-4-yl-piperazine hydrochloride as colorless needle-like crystals.

Aufarbeitung

  1. customthe solvent was evaporated under reduced pressure
  2. additionEthyl acetate was added to the obtained residue
  3. customprecipitated crystals
  4. customwere obtained by filtration
  5. customRecrystallization

Quellen und Nachweise

ORD-Eintrag
ord-b46f908a3ccb4f26adb9e601a1172dab
Quelldatensatz
uspto-grants-2011_12
Patentnummer
US08071600B2

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