6-Methoxy-2-hexanone → HCID 86639839, Verbindung

HRID 656239Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 656239
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7](=[O:9])[CH3:8].[Cl-:10].[Li+]>CN(C)C=O.O.[Cu](Cl)Cl>[Cl:10][CH:6]([CH2:5][CH2:4][CH2:3][O:2][CH3:1])[C:7](=[O:9])[CH3:8]

Komponenten

5

Edukt 2

HCID 344156-Methoxy-2-hexanoneHCID 433294Lithium Chloride

Produkt 1

HCID 86639839HCID 86639839, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 16219111Copper(II) chloride dihydrateKatalysatorHCID 6228DimethylformamideLösungsmittel2×

Reaktionsbedingungen

Temperatur
85 °C

Versuchsvorschrift

1.5 mol of 6-methoxyhexan-2-one [29006-00-6] are added to a mixture of 3.6 mol of copper(II) chloride hydrate and 1.8 mol of lithium chloride in 900 ml of N,N-dimethylformamide at 80° C. The reaction mixture is stirred at 80-90° C. for 1 hour. 900 g of ice are added, and the precipitate is dissolved by adding N,N-dimethylformamide. Extraction with pentane (6×) is carried out. The combined organic phases are washed with water, dried over sodium sulphate and fractionated in vacuo. The title compound is identified by means of the Rf.

Aufarbeitung

  1. dissolutionthe precipitate is dissolved
  2. extractionExtraction with pentane (6×)
  3. washThe combined organic phases are washed with water
  4. dry with materialdried over sodium sulphate

Quellen und Nachweise

ORD-Eintrag
ord-74c7c43ec2a34bb98c762563df4e4925
Quelldatensatz
uspto-grants-2011_12
Patentnummer
US08071651B2

Notizen zur Reaktion

Wird geladen…