Sodium hydride → 2-(5,7-Dimethyl-2-oxo-3-{[(7S)-2'-oxo-1',2',6,8-tetrahydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridin]-2-yl]methyl}-2,3-dihydro-1H-benzimidazol-1-yl)-N,N-dimethylacetamide

Reaktionsgleichung

[CH3:1][C:2]1[CH:17]=[C:16]([CH3:18])[C:5]2[N:6]([CH2:10][C:11]([N:13]([CH3:15])[CH3:14])=[O:12])[C:7](=[O:9])[NH:8][C:4]=2[CH:3]=1.[H-].[Na+].O[CH2:22][C:23]1[CH:32]=[CH:31][C:30]2[C:25](=[CH:26][C:27]3[CH2:44][C@:34]4([C:42]5[C:37](=[N:38][CH:39]=[CH:40][CH:41]=5)[NH:36][C:35]4=[O:43])[CH2:33][C:28]=3[CH:29]=2)[N:24]=1>CN(C=O)C>[CH3:1][C:2]1[CH:17]=[C:16]([CH3:18])[C:5]2[N:6]([CH2:10][C:11]([N:13]([CH3:14])[CH3:15])=[O:12])[C:7](=[O:9])[N:8]([CH2:22][C:23]3[CH:32]=[CH:31][C:30]4[C:25](=[CH:26][C:27]5[CH2:44][C@:34]6([C:42]7[C:37](=[N:38][CH:39]=[CH:40][CH:41]=7)[NH:36][C:35]6=[O:43])[CH2:33][C:28]=5[CH:29]=4)[N:24]=3)[C:4]=2[CH:3]=1