HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Paclitaxel → Baccatin Iii
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Paclitaxel | HCID 36314 | — |
| Edukt | 7-Epi-Taxol | HCID 184492 | — |
| Produkt | Baccatin Iii | HCID 65366 | — |
Reaktionsschritte
Degradation products were formed in the same proportions as in the experiments conducted under room temperature but in significantly lower quantities. Again, 7-epi-taxol was the main degradation product of paclitaxel (10% at pH 8.0). Baccatin III and 10-deacethyltaxol were formed for about 5 to 6% at pH 8.0. Found unknown substances were the same.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08075913B2 |
| Quelldatensatz | uspto-grants-2011_12 |
| ORD ID | ord-19871fd22d5c45abb55394df7344fe92 |
| Quellennotiz | uspto-grants-2011_12 |