HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Isopropyl isocyanate → 2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl-N'-(1-methylethyl)urea
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Isopropyl isocyanate | HCID 61277 | — |
| Edukt | 5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine | HCID 162203 | — |
| Lösungsmittel | Acetonitrile | HCID 6342 | — |
| Produkt | 2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl-N'-(1-methylethyl)urea | HCID 23452144 | 93,7% |
Reaktionsschritte
2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine (2.14 g) and isopropylisocyanate (0.89 g) were dissolved in acetonitrile and allowed to stand overnight. Solvents were removed and the residue recrystallised from methanol:ether to give N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl-N'-(1-methylethyl)urea as crystals m.p. 65°-67° (2.8 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04128658 |
| Quelldatensatz | uspto-grants-1978_12 |
| ORD ID | ord-ba9a62af5dc1452292d5c5c2f0e4d526 |
| Quellennotiz | uspto-grants-1978_12 |