Carbonochloridothioic acid, S-phenyl ester → HCID 85920205, Verbindung

HRID 65798

Reaktionsgleichung

Reaktionsgleichung von HRID 65798
[NH2:1][C:2]([CH3:6])([CH3:5])[C:3]#[N:4].[C:7]1([S:13][C:14](Cl)=[O:15])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>O1CCOCC1>[C:3]([C:2]([NH:1][C:14](=[O:15])[S:13][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:6])[CH3:5])#[N:4]

Komponenten

4

Edukt 2

HCID 83493Carbonochloridothioic acid, S-phenyl esterHCID 880222-Amino-2-methylpropionitrile

Produkt 1

HCID 85920205HCID 85920205, VerbindungAusbeute 30,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel2×

Versuchsvorschrift

3.4 g. (0.04 mole) of 2-amino-2-methylpropanonitrile are dissolved in 10 ml. of dioxane and a solution of 3.2 ml. (0.2 mole) of (phenylthio)carbonyl chloride in 10 ml. of dioxane is added. After stirring for one hour at room temperature, the reaction mixture is filtered, the filtrate is concentrated, and the solid residue is recrystallized from a small amount of toluene to yield 2.7 g of (1-cyano1-methylethyl)carbamothioic acid, S-phenyl ester; m.p. 152°-155°.

Aufarbeitung

  1. filtrationthe reaction mixture is filtered
  2. concentrationthe filtrate is concentrated
  3. customthe solid residue is recrystallized from a small amount of toluene

Quellen und Nachweise

ORD-Eintrag
ord-f4ecdca4ae7c4dfea97c7b618470ddd7
Quelldatensatz
uspto-grants-1978_12
Patentnummer
US04128723

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