HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl Thioglycolate → Methyl 4-fluoro-1-benzothiophene-2-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl Thioglycolate | HCID 16907 | — |
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 2,6-Difluorobenzaldehyde | HCID 136284 | — |
| Produkt | Methyl 4-fluoro-1-benzothiophene-2-carboxylate | HCID 2783209 | — |
Reaktionsschritte
Using 5.0 g (35.2 mmol) of 2,6-difluorobenzaldehyde, 2.11 g (52.8 mmol) of sodium hydride (60% pure) and 4.11 g (38.7 mmol) of methyl mercaptoacetate, 5.61 g (72.8% of theory) of the title compound are obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08076355B2 |
| Quelldatensatz | uspto-grants-2011_12 |
| ORD ID | ord-1d9c6779045149128c3ab3d1cf0d0b33 |
| Quellennotiz | uspto-grants-2011_12 |