[1,1'-Biphenyl]-4-ol, 4'-(1,1-dimethylethyl)- → racemic 3-{4-[1-(4'-tert-Butyl-biphenyl-4-yloxymethyl)-heptyl]-benzoylamino}-propionic acid
Reaktionsgleichung
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].C[O:19][C:20](=[O:41])[CH2:21][CH2:22][NH:23][C:24](=[O:40])[C:25]1[CH:30]=[CH:29][C:28]([CH:31]([CH2:38]O)[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])=[CH:27][CH:26]=1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:12]=[CH:13][C:14]([O:17][CH2:38][CH:31]([C:28]3[CH:27]=[CH:26][C:25]([C:24]([NH:23][CH2:22][CH2:21][C:20]([OH:41])=[O:19])=[O:40])=[CH:30][CH:29]=3)[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])=[CH:15][CH:16]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:2])[CH3:3]Komponenten
3
Versuchsvorschrift
The title compound is prepared by essentially following the procedures as described in Example 8, using 4′-tert-butyl-biphenyl-4-ol and 3-[4-(1-hydroxymethyl-heptyl)-benzoylamino]-propionic acid methyl ester as starting materials. MS (ES): 528.3 [M+H]−.
Quellen und Nachweise
- ORD-Eintrag
- ord-5e000b2118594750957675187120e811