HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Cyclopropyl-4,6-bis-trifluoromethyl-benzoic acid → 2-Cyclopropyl-N-((cis)-2-pyrrolidin-1-yl-cyclohexyl)-4,6-bis-trifluoromethyl-benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Cyclopropyl-4,6-bis-trifluoromethyl-benzoic acid | HCID 58167765 | — |
| Edukt | cis-2-Pyrrolidin-1-yl-cyclohexylamine dihydrochloride | HCID 66680564 | — |
| Produkt | 2-Cyclopropyl-N-((cis)-2-pyrrolidin-1-yl-cyclohexyl)-4,6-bis-trifluoromethyl-benzamide | HCID 51001328 | — |
Reaktionsschritte
The title compound, white solid, MS: m/e=449.3 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclohexylamine dihydrochloride (intermediate F) and 2-cyclopropyl-4,6-bis-trifluoromethyl-benzoic acid (intermediate AN).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08080541B2 |
| Quelldatensatz | uspto-grants-2011_12 |
| ORD ID | ord-294afdd55473481ea83bac75f9291707 |
| Quellennotiz | uspto-grants-2011_12 |