1-Piperazinylpyrazine → (3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-(2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)methanone

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-Piperazinylpyrazine	HCID 2734639	—
Edukt	3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid	HCID 58327807	—
Produkt	(3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-(2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)methanone	HCID 58327941	—

Reaktionsschritte

3-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 2-(1-piperazinyl)pyrazine as in General Procedure 10 to give the title compound. LCMS: m/z=593.97 (M+H+); retention time=0.78 minutes.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08080561B2
Quelldatensatz	uspto-grants-2011_12
ORD ID	ord-81af611fe3fe4e20995fac659a80f5ca
Quellennotiz	uspto-grants-2011_12