2-Methyl-4-(piperazin-1-yl)quinoline → (4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-Methyl-4-(piperazin-1-yl)quinoline	HCID 702318	—
Edukt	4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid	HCID 46906718	—
Produkt	(4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone	HCID 58327833	—

Reaktionsschritte

4-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 2-methyl-4-(1-piperazinyl)quinoline as in General Procedure 10 to give the title compound. LCMS: m/z=656.96 (M+H+); retention time=0.62 minutes.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08080561B2
Quelldatensatz	uspto-grants-2011_12
ORD ID	ord-129a73f5808c4224bc34ab8545139382
Quellennotiz	uspto-grants-2011_12